I am indebted to all my teachers and mentors. I would like to thank Dr. Neil Gelman at The Western University (Canada) for introducing me into the MRI field and inspiring me for developing the MatrixUser project. I would also like to thank Drs. Wally Block and Richard Kijowski at The University of Wisconsin-Madison (USA) who guide me to acquire knowledge of MR sequence design and medical image application. My gratitude is owed to Dr. Alexey Samsonov at The University of Wisconsin-Madison (USA) for inspiring me about MT functions. Many people also contribute significantly to the MRiLab project through publishing free code online which largely extends MRiLab functionality, in particular, Dr. Tilman Johannes Sumpf at Biomedizinische NMR Forschungs GmbH (Germany), Dr. John Pauly and Dr. Brian Hargreaves at Stanford University (USA). Finally, my appreciation goes to my wife Zhaoye Zhou who supports me for finishing the whole project.